Pricing
One architecture, all plans.
Every plan uses the same physics-valid arch. Higher tiers add enterprise features: custom training on your private molecules, on-prem deployment, compliance, and dedicated support.
Free
Explore the API
$0
- ✓20 requests / day
- ✓All public molecules
- ✓Community support
- ✓Watermarked outputs
Starter
Solo comp chem consultants
$499/ month
- ✓10,000 requests / day
- ✓Full public catalog + tautomer prep
- ✓Batch API (up to 1,000 SMILES / request)
- ✓SDF / PDB / MOL2 downloads
- ✓Email support (48hr response)
MOST POPULAR
Pro
Series A-C biotech comp chem teams
$2,499/ month
- ✓100,000 requests / day
- ✓Priority queue (no cold-starts)
- ✓Docking-ready outputs (Vina / Glide)
- ✓Ring pucker + macrocycle mode
- ✓Slack support channel
- ✓99.5% SLA
Team
Series C+ biotech, mid-pharma
$9,999/ month
- ✓1,000,000 requests / day
- ✓Custom molecule training on your SMILES
- ✓On-prem Docker deployment
- ✓Dedicated support engineer
- ✓99.9% SLA + quarterly review
- ✓Compliance: SOC2 in progress
Enterprise
Big pharma, contract research
Custom
- ✓Unlimited requests (fair use)
- ✓Private dedicated Physon instance
- ✓Custom architecture fine-tuning
- ✓SOC2 + GDPR + audit logs
- ✓Named account manager, phone support
- ✓99.95% SLA
Annual billing
Save 20% with annual commitment on Starter–Team tiers. Enterprise contracts are negotiated per engagement.
Fair use
Request limits are per API key per calendar day. Batch endpoints count once per batch, not per SMILES.
Overage pricing
Beyond monthly quota: $0.001 / molecular request, $0.005 / 3D request. Metered via Stripe.